≠≠What'sNEW in Cosmic Ancestry, beginning Sep 2022


18 Nov 2022
...what's needed is proof-by-example (quarantined biology) or proof-of-principle (digitally quarantined computer models). This is my refrain to the mainstream theory of evolution, because these proofs are conspicuously missing. Although the "mainstream" is actuallty quite fractured nowadays, it unanimously clings to a "core belief," that life can originate from ordinary chemicals and make ongoing macroevolutionary progress on a quarantined, initially lifeless planet. Without proof, it is reasonable to doubt the core belief. In fact, half the population, including many well-informed experts, do doubt it.

I have promoted tests that might satisfy these lacks, without serious takers. And I have often discussed the lack of proof with mainstream biologists. These discussions have not been fruitful. The issue is not squarely faced, or evidence for historical evolution is touted as proof. Doubters are dismissed as uninformed or unscientific. Many experts who share the doubts do not participate in the discussion because they have learned that it is unproductive and uncivil. I'm getting there, following another lengthy exchange, this time with a published theoretical biologist. I spent a lot of effort on this cross-paradigm conversation, but it went nowhere. My side of it is the latest entry in "Replies".
Sep - Nov 2022: emails with Adam S. Wilkins.

14 Nov 2022What'sNEW about HGT
The importance of HGT among prokaryotes is already well-established, but this example deserves notice:
Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair by Andrew S. Lang, PLoS Biol, 08 Nov 2022; re: Prophage-like gene transfer agents promote Caulobacter crescentus survival and DNA repair during stationary phase by Kevin Gozzi et L., PLoS Biol, 03 Nov 2022.
10 Mar 2021: New genes can be acquired only via HGT..., affirming HGT among prokaryotes, with links.

Kurt Vonnegut (from The New York Times)
11 Nov 2022
...scientists are pretending they have the answer ...when natural selection couldn't possibly have produced such a machine. — Kurt Vonnegut, 2006
Remembering author Kurt Vonnegut, who would have turned 100 on Friday, 7-minute excerpt of interview, Morning Edition, NPR, 11 Nov 2022.

08 Nov 2022
The Whole Truth - book cover The Whole Truth, by P.J.E Peebles, is an instructive story about the currently favored model for cosmology. Peebles earned a Nobel prize in 2019 for his contributions to that model, designated ΛCDM, "lambda cold dark matter." In it, today's universe grew from an earlier, hot, dense phase and most of its mass appears to be non-baryonic. These ideas are supported by multiple lines of evidence from diverse sources using different methods, he explains. The presentation is forceful, but polite and undogmatic. For example, he admits that different methods find different values for the Hubble constant. I learned a lot from the book, and I am grudgingly accepting the case for a hot dense earlier phase of the universe. And some of Peebles, I confess, went over my head on first reading. Don't ask me to explain "tilt".

Fortunately, Peebles also wonders what the universe was doing before it was expanding, and says that we have no coherent theory of the "beginning" of the universe. (A beginning from a super-hot single point, with nowhere to hide, would sterilize everything.)

I was pleased to learn that Mach's challenging skepticism had lasting influence, and to learn more about Einstein's path to General Relativity. George Gamow's role in the development of today's cosmology was bigger than I knew. Fred Hoyle's multiple contributions are acknowledged and explained. Cosmology is a collaborative enterprise, and Peebles knows who contributed what, and when.

Peebles has a lot to observe about how science advances. Some discoveries come almost simultaneously from different scientists, "Merton's multiples," he names them. Some ideas are originally accepted for their elegance and simplicity. Some insights are simply "in the air." Major breakthroughs usually come from "small science," whose papers have only a few authors. While his examples come from cosmology, the book is largely about the logic and philosophy of science.

I also think about that subject, with examples from a different field, evolution. The contrast is striking:

While cosmologists may work independently, they heed others and notice evidence from any source that may be relevant. If an anomaly arises, it is investigated. Resolving differences is an unstated, obvious goal. And the assumptions underlying the whole enterprise are not exempt from scrutiny. This freedom keeps the subject healthy and lively. By comparison, today's theory of evolution is ridgidly blindered, gridlocked.

Peebles writes "a 'persuasive case' [applies] to theories that pass enough tests of prediction to persuade the community to accept the theory...." By that criterion, the Modern Synthesis (including EES, etc.) is obviously not persuasive. Its defenders respond that the unpersuaded are not members of the "community."

"At the heart of the science wars is surely the difficulty of communication between different cultures with different traditions," Peebles says, referring to conflict with "anti-science." A skeptical alternative such as cosmic ancestry is not "anti-science," but mainstream biology frames all skepticism that way. "The mismatch makes fertile ground for misunderstandings," Peebles concludes. These words come from a distinguished scientist who well understands the practice of science. Highly recommended.

The Whole Truth: A Cosmologistís Reflections on the Search for Objective Reality by P. J. E. Peebles, Princeton University Press, 02 Aug 2022.
21 Nov 2019: comments from an interview with James Peebles.
The End and the Big Bang includes evidence inconsistent with a hot big bang from a single point.

04 Nov 2022What'sNEW about HGT |
...the whitefly... has acquired no less than 49 genes through at least 24 events of HGT from plant sources.
Multiple Horizontal Acquisitions of Plant Genes in the Whitefly Bemisia tabaci by Clément Gilbert and Florian Maumus, Genome Biology and Evolution, Oct 2022.
26 Mar 2021: more about transferred whitefly genes.
Viruses and Other Gene Transfer Mechanisms has a primer and many updates with examples.

01 Nov 2022
Science without humility and community slows our collective understanding.
Weldon, Bateson, and the origins of genetics: Reflections on the unraveling and rebuilding of a scientific community by Lea K. Davis, PLoS Gen, 27 Oct 2022.

30 Oct 2022What'sNEW about HGT |
Science writers for Quanta take a wide look at HGT, with references and insights from recognized experts.
How Genes Can Leap From Snakes to Frogs in Madagascar by Veronique Greenwood, Quanta, 27 Oct 2022. Quanta Magazine
28 Apr 2022: about the original study of retroposons transferred from snakes to frogs.
Viruses... cites more than 2,000 examples of HGT, including every gene category.
Thanks Thanks, Google Alerts and Adam S. Wilkins. Adam, please notice also:
Scientists Catch Jumping Genes Rewiring Genomes, by Max Kozlov, Quanta, 12 May 2021.

30 Oct 2022
On Christmas Eve, 2021, the seismometer on the Mars Insight Lander detected an unusual jolt. Photos from the Mars Reconnaissance Orbiter, examined later, provided a sure explanation. A fresh meteor scar on Amazoni Planitia, photographed on Christmas Day, had not been there in the photo taken the day before. Later study of high-resolution images showed that chunks of water-ice had been scattered by the impact. NASA did not anticipate finding water so close to the equator.
Impact crater on Mars

Surface waves and crustal structure on Mars by Doyeon Kim et al., and
Largest recent impact craters on Mars: Orbital imaging and surface seismic co-investigation by L. V. Posiolova et al., Science, 27 Oct 2022.
...It Came From Space. by Kenneth Chang, The New York Times, 27 Oct 2022.
Thanks Thanks, Rob Cooper. Life on Mars!, cites various, noteworthy evidence.

27 Oct 2022
Extremophiles on Mars could survive for hundreds of millions of years by Keith Cooper, Space,com +Scientific American, 25 Oct 2022; re:
Effects of Desiccation and Freezing on Microbial Ionizing Radiation Survivability... by William H. Horne et al., Astrobiology, online 25 Oct 2022. Desiccation and freezing greatly increased radiation survival....
Bacteria..., and Life on Mars!, have background and updated information.
Thanks Thanks, Google Alerts and George Nickas.

09 Oct 2022
process of sporulation and return to germination adapted from Nature Many bacteria can enter a state of dormancy by the process of Sporulation (right side of illustration). As endospores, they can survive many environmental threats and persist indefinitely with no metabolism. When it's safe again, Germination (red arrow) is initiated, and Metabolism and Reproduction resume (left).

New research suggests that the membrane protecting the spore stores electrical energy as a "biological capacitor," accumulating and integrating signals from the environment while the spore is chemically inert. Upon reaching a threshold, the capacitor triggers Germination and the cell resumes normal life. Of course, this would be crucial for panspermia.

...short nutrient pulses result in step-like changes in the electrochemical potential of persistent spores. During dormancy, spores thus gradually release their stored electrochemical potential to integrate extracellular information over time. It would be hard to invent a neo-darwinian explanation for the programming underlying this capability.

Electrochemical potential enables dormant spores to integrate environmental signals by Kaito Kikuchi et al., Science, 06 Oct 2022.
An electric alarm clock for spores by Jonathan Lombardino and Briana M. Burton, Science, 06 Oct 2022.
...How Dormant Bacteria Calculate Their Return to Life, UC San Diego (+Newswise), 06 Oct 2022.
Bacteria: The Space Colonists has background and updates about their hardiness.
Robust Software Management begins with a brief discussion of endospores.

04 Oct 2022
Cosmic ancestry, if even approximately correct, would require a Kuhnian paradigm shift in biology. Mainstream biology is not ready to consider a theory so different. For now, the occasional cross-paradigm conversations may be instructive to notice. They illustrate how difficult it is to reach understanding when underlying beliefs are so divergent. Here are some recent ones, posted in "Replies."
Sep 2022: Raju Pookottil, a member of "The Third Way of evolution," reacts to cosmic ancestry.
Jun-Sep 2022: My side of a conversation with biochemist and molecular biologist James A. Shapiro (excerpt below).

...Think with me for a moment about quantum theory. It began by creating a canyon-size gap in physics. But Bohr and Einstein never quit talking. Crucial experiments (Bell's Inequality) seemed to leave the old philosophy unworkable, yet questions remained unsettled until every possible alternative explanation had been explored. Turns out, yes, the old philosophy is unworkable. A new philosophy must replace it. And no one thinks this philosophy is complete. Dialog was fruitful and continues to be.

Now think about today's theory of evolution. There are profound disagreements, but each side talks only with itself. Experiments (Lenski et al.) are interpreted in conflicting ways, without collaborative scrutiny. In my opinion, scientific principles and practice are being ignored. If science is abandoned, you "hand the victory" to your anti-science opponents, to paraphrase Fred Hoyle.

04 Oct 2022 What'sNEW about HGT |
Roy Kirsch et al., PNAS, 26 Sep 2022. Horizontal gene transfer (HGT) provides an evolutionary shortcut for recipient organisms to gain novel functions. Although reports of HGT in higher eukaryotes are rapidly accumulating, in most cases the evolutionary trajectory, metabolic integration, and ecological relevance of acquired genes remain unclear.
Metabolic novelty originating from horizontal gene transfer is essential for leaf beetle survival by Roy Kirsch et al., doi:10.1073/pnas.2205857119, PNAS, 26 Sep 2022.

Also, a stinkbug benefits from cross-kingdom HGT. It seems to be everywhere.
A new antimicrobial peptide, Pentatomicin, from the stinkbug Plautia stali, by Yudai Nishide et al., Nature, 04 Oct 2022. Notably, orthologous sequences were also detected from a horseshoe crab, cyanobacteria and proteobacteria, suggesting the possibility of inter-domain horizontal gene transfers of Pentatomicin and allied protein genes.
Viruses... cites more than 2,000 examples of HGT, crossing all kingdoms.
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